Providing access to frontier AI systems raises complex questions around dual-use science and catastrophic risk. How should models respond to requests involving chemical synthesis, biological experimentation, or pathogen research? Where is the boundary between legitimate scientific inquiry and information that could enable misuse? How do we design policies that meaningfully reduce risk without unnecessarily restricting beneficial research?

This is a senior role in which you’ll help shape policy creation and development at OpenAI for addressing biological and chemical risks. You will develop structured policy frameworks and taxonomies to guide safe model behavior. This role sits at the intersection of biosecurity expertise, AI safety research, and policy design. You will help ensure that frontier AI systems can support beneficial life sciences research, such as drug discovery, public health, and biosafety, while reducing the risk that these capabilities could be misused.

Our relevant publications:

Preparedness framework

Preparing for future AI capabilities in biology

Safety evaluations hub

OpenAI GPT5 System Card

Evaluating Fairness in ChatGPT

Improving Model Safety Behavior with Rule-Based Rewards

OpenAI Model Spec

Your Responsibilities:

Design and maintain model policies governing chemical and biological risk, defining how models should safely handle dual-use scenarios.

Model Policy, Chemical & Biological Risk

Responsibilities

Benefits

Company

Openai

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